For me, there is no way that Epicurean philosophy can be understood properly without always keeping in mind this core idea: that we are mortal and that we need to "live like we are dying" - because we are.
I think that there are many ways to expand upon this, because we are also animals who have a life expectancy depending on our health. So we need to take that into consideration. If a doctor visit reveals matastesized cancer then that person is going to make different choices than a person who has potentially 50 more years to live.
It costs money to do things like travel and going sky-diving (or other activities of choice) and so it's a balance between enjoying one's health and vitality (being active and doing things) and considering one's life expectancy. But when you realize what is most important to you, then you can determine the "opportunity cost" involved. And we only have so much time, so we have to make peace with that as well, since it is possible to have lots of projects that we want to finish, but that we may not actually be able to finish them all.
QuoteIn microeconomic theory, the opportunity cost of a choice is the value of the best alternative forgone where, given limited resources, a choice needs to be made between several mutually exclusive alternatives. Assuming the best choice is made, it is the "cost" incurred by not enjoying the benefit that would have been had by taking the second best available choice.[1] The New Oxford American Dictionary defines it as "the loss of potential gain from other alternatives when one alternative is chosen." As a representation of the relationship between scarcity and choice,[2] the objective of opportunity cost is to ensure efficient use of scarce resources.[3] It incorporates all associated costs of a decision, both explicit and implicit.[4] Thus, opportunity costs are not restricted to monetary or financial costs: the real cost of output forgone, lost time, pleasure, or any other benefit that provides utility should also be considered an opportunity cost.
Source: Wikipedia
Regarding the quote from Lucretius, Book 3 :1053 - that is a description of a person who is "lost" and feels restless, anxious, and bored. And that individual definetly needs to take a metaphorical drink of wormwood (rimmed with honey!). The wormwood is bitter and so is the contemplation on one's own death. And this type of person is going to likely need to "take the treatment" multiple times.
Perhaps talking and eating cake at a "death cafe" meeting.