I've never experienced psychedelics, but going by report I would analyze them under the rubric I outlined above. Only in this case, instead of the brain 'involuntarily adding a layer of interpretation', it cakes it on so thickly that the reported sensation is altered completely before the conscious mind has time to act upon it. Here's a thought experiment: suppose you had one optic nerve simultaneously grafted to two different brains. One brain is high, the other is clear--what does the clear brain see?
...I've been up since 5 pm.